Botulinum toxin A (Merz Pharma)

A型肉毒毒素（Merz Pharma）

Report date: 2026/04/28 20:00:22

Base Information

Drug NameBotulinum toxin A (Merz Pharma)
Drug Alias NameBotulinum neurotoxin type A free from complexing protein-Merz Pharmaceuticals注射用A型肉毒毒素（150KD,不含复合蛋白）Incobotulinum toxin AincobotulinumtoxinAXeomin +[9] 
ClassificationBiologics > Protein drugs > ToxinNatural product/Extract > Microbial extract
Mechanisms of ActionSynaptosomal-associated protein 25 inhibitors
TargetsSynaptosomal-associated protein 25
Therapy Area/IndicationsNasolabial fold wrinklesUpper and lower limb spasticityGlabellar lines +[38] 
Global Approved IndicationsNasolabial fold wrinklesUpper and lower limb spasticityBlepharospasm +[4] 
Approved Indications in ChinaNasolabial fold wrinkles
Original Approved Country/TerritoryUnited States
Original Approved Date2010/07/30
Country/TerritoryCzechiaBelgiumCanada +[32] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesBiotecon Therapeutics
China Registration ClassN/A

Develop Information

Active CompaniesManhattan Physical Medicine And Rehabilitation, LlpMerz PharmaUniversita di Verona +[16] 
Inactive CompaniesCairo UniversityBiolab Sanus Farmaceutica LlcYale University +[12] 
Active IndicationsNasolabial fold wrinklesUpper and lower limb spasticityGlabellar lines +[19] 
Inactive IndicationsUpper limb spasticityPainAtrial Fibrillation +[19] 

Other Information

ATC CodeM03AX01
Related LinksWikipedia