Alectinib Hydrochloride

阿来替尼盐酸盐

Report date: 2024/09/29 17:48:36
NME

Base Information

Drug NameAlectinib Hydrochloride
Drug Alias NameAlectinibum艾乐替尼盐酸盐阿雷替尼盐酸盐Alectinib盐酸阿雷替尼 +[14] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionTyrosine-protein kinase receptor RET inhibitorsAnaplastic lymphoma kinase inhibitors
TargetsAnaplastic lymphoma kinaseTyrosine-protein kinase receptor RET
Therapy Area/IndicationsBrain metastasesSolid tumoursLymphoproliferative Disorders +[40] 
Global Approved IndicationsCarcinoma, Non-Small-Cell LungLung Neoplasms
Approved Indications in ChinaLung Neoplasms
Original Approved Country/TerritoryJapan
Original Approved Date2014/07/04
Country/TerritoryCzechiaBelgiumBosnia and Herzegovina +[44] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesChugai Pharmaceutical Co Ltd
China Registration ClassN/A

Develop Information

Active CompaniesChugai Pharmaceutical Co LtdInstituto Nacional De CancerologiaF. Hoffmann-La Roche Ag +[10] 
Inactive CompaniesDana-Farber Cancer Institute
Active IndicationsBrain metastasesSolid tumoursLymphoproliferative Disorders +[14] 
Inactive IndicationsCentral Nervous System DiseasesRespiratory Tract DiseasesHepatic Insufficiency +[26] 

Other Information

ATC CodeL01XE
Related LinksWikipediaDrugBankKEGG