Carglumic Acid

卡谷氨酸

Report date: 2023/07/04 14:39:09
NMEFirst In Class

Base Information

Drug NameCarglumic Acid
Drug Alias Name卡哥鲁酸acide carglumiqueacidum carglumicumN-carbamyl-L-glutamic acidUdecane +[7] 
ClassificationSmall molecules > Amino acid supplement, Lipids and Vitamins
Mechanisms of ActionCarbamoyl phosphate synthetase 1 activators
TargetsCarbamoyl phosphate synthetase 1
Therapy Area/IndicationsMethylmalonic acidaemiaHyperammonemiaPropionic Acidemia +[10] 
Global Approved IndicationsHyperammonemiaPropionic AcidemiaAmino Acid Metabolism, Inborn Errors
Approved Indications in ChinaHyperammonemia
Original Approved Country/TerritoryEU
Original Approved Date2003/01/24
Country/TerritoryUnited StatesEUMainland China +[4] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesPola ChemicalOrphan Europe
China Registration ClassN/A

Develop Information

Active CompaniesPola ChemicalEton Pharmaceuticals IncRecordati Rare Diseases Inc +[4] 
Inactive CompaniesChildren'S National Research InstituteEunice Kennedy Shriver National Institute Of Child Health And Human DevelopmentStanford University +[8] 
Active IndicationsHyperammonemiaPropionic AcidemiaAmino Acid Metabolism, Inborn Errors
Inactive IndicationsMethylmalonic acidaemiaMetabolism, Inborn ErrorsOrnithine Carbamoyltransferase Deficiency Disease +[7] 

Other Information

ATC CodeA16AA05
Related LinksWikipediaDrugBankKEGG