Mechlorethamine Hydrochloride

盐酸氮芥

Report date: 2022/03/23 14:31:07
NME

Base Information

Drug NameMechlorethamine Hydrochloride
Drug Alias NameNitrogen mustard topical gel氮芥Chlormethine Hydrochloride氮芥盐酸盐Topical nitrogen mustard +[15] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionAlkylating agentsDNA inhibitors
TargetsDNA
Therapy Area/IndicationsAscitesCarcinoma, BronchogenicPolycythemia Vera +[10] 
Global Approved IndicationsAscitesCarcinoma, BronchogenicPolycythemia Vera +[8] 
Approved Indications in ChinaAscitesHodgkin DiseaseLymphoma
Original Approved Country/TerritoryUnited States
Original Approved Date1949/03/15
Country/TerritoryUnited StatesEUMainland China
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesRecordati Spa
China Registration ClassN/A

Develop Information

Active CompaniesKyowa KirinJuniper Biologics Pte LtdHelsinn +[5] 
Inactive CompaniesRecordati Rare Diseases IncSidney Kimmel Cancer Center At Thomas Jefferson UniversityThomas Jefferson University +[4] 
Active IndicationsAscitesMycosis FungoidesLymphoma, T-Cell +[5] 
Inactive IndicationsCarcinoma, BronchogenicPolycythemia VeraLymphoma, T-Cell, Cutaneous +[5] 

Other Information

ATC CodeL01AA05
Related LinksWikipediaDrugBankKEGG