4D-110

N/A

Report date: 2025/07/04 20:00:55

Base Information

Drug Name4D-110
Drug Alias NameAAV capsid variant (4D-R100) carrying a transgene encoding a codon-optimized human CHM gene
ClassificationCell and gene therapy > Gene therapy > Viral vector-based gene therapy > Adeno-associated virus vector
Mechanisms of ActionRab proteins geranylgeranyltransferase component A 1 gene transference
TargetsRab proteins geranylgeranyltransferase component A 1
Therapy Area/IndicationsChoroideremia
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryUnited States
CombinationsNo
Global Highest StatusPhase 1 Clinical
Highest Status in ChinaN/A
Originator Companies4d Molecular Therapeutics Inc
China Registration ClassN/A

Develop Information

Active Companies4d Molecular Therapeutics IncF. Hoffmann-La Roche Ltd
Inactive CompaniesN/A
Active IndicationsChoroideremia
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksN/A