Iobenguane I-131

碘[131I]苄胍

Report date: 2025/11/25 15:53:22
NME

Base Information

Drug NameIobenguane I-131
Drug Alias Name碘[131I]苄胍131I-iobenguane - Progenics Pharmaceuticals3-Iodobenzylguanidine (131I)Ultratrace iobenguane I 131131I-m-Iodobenzylguanidine +[18] 
ClassificationSmall moleculesRadiation-emitting products > Nuclides > Iodine > 131IRadiation-emitting products > Radioactive therapeutic agent +[4] 
Mechanisms of ActionMitochondrial complex I (NADH dehydrogenase) inhibitors
TargetsMitochondrial complex I (NADH dehydrogenase)
Therapy Area/IndicationsDiagnostic agentsNeoplasm MetastasisPheochromocytoma +[6] 
Global Approved IndicationsDiagnostic agentsPheochromocytomaNeuroblastoma
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date1994/03/25
Country/TerritoryUnited StatesMainland ChinaJapan
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaPhase 3 Clinical
Originator CompaniesUniversity Of MichiganFujifilm Corp
China Registration ClassN/A

Develop Information

Active CompaniesFujifilm CorpHta Co Ltd
Inactive CompaniesPharmalucence IncUniversity Of California San FranciscoThe University Of Texas MD Anderson Cancer Center +[6] 
Active IndicationsPheochromocytomaParaganglioma
Inactive IndicationsDiagnostic agentsNeoplasm MetastasisNeuroendocrine Tumors +[4] 

Other Information

ATC CodeV09IX
Related LinksWikipediaDrugBankKEGG