Lotilaner

洛替拉纳

Report date: 2026/05/06 20:02:28
NMEFirst In Class

Base Information

Drug NameLotilaner
Drug Alias NameSMisoxamXDEMVYTP-03AHC-2224920IOB-920 +[11] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of Actionmites GABA-gated chloride channel inhibitors
Targetsmites GABA-gated chloride channel
Therapy Area/IndicationsDemodex blepharitisRosaceaMeibomian Gland Dysfunction +[5] 
Global Approved IndicationsDemodex blepharitis
Approved Indications in ChinaDemodex blepharitis
Original Approved Country/TerritoryUnited States
Original Approved Date2023/07/24
Country/TerritoryCanadaUnited StatesMainland China
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesElanco Tiergesundheit Ag
China Registration ClassN/A

Develop Information

Active CompaniesBlackstone Life SciencesTarsus Pharmaceuticals IncGrand Pharmaceutical （China） Co Ltd
Inactive CompaniesNextPharma OyLianBio Development (HK) LtdShanghai LianBio Development Co Ltd
Active IndicationsDemodex blepharitisRosaceaMeibomian Gland Dysfunction +[5] 
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksWikipediaDrugBankKEGG