PEN-866

N/A

Report date: 2026/02/06 20:01:23
NME

Base Information

Drug NamePEN-866
Drug Alias NamePEN-866STA-8666SDC-TRAP-0063STA-12-8666
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionDNA topoisomerase I inhibitorsHeat shock protein HSP90 inhibitors
TargetsHeat shock protein HSP90DNA topoisomerase I
Therapy Area/IndicationsGastroesophageal Junction NeoplasmsSolid tumoursEndometrial Neoplasms +[14] 
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryUnited StatesMainland China
CombinationsNo
Global Highest StatusPhase 1 Clinical
Highest Status in ChinaPhase 1 Clinical
Originator CompaniesMadrigal Pharmaceuticals IncTarveda Therapeutics Inc
China Registration ClassN/A

Develop Information

Active CompaniesSciclone Pharmaceuticals (Holdings) LtdTarveda Therapeutics Inc
Inactive CompaniesNational Cancer Institute
Active IndicationsSmall Cell Lung CarcinomaCarcinoma, Non-Small-Cell Lung
Inactive IndicationsGastroesophageal Junction NeoplasmsSolid tumoursEndometrial Neoplasms +[12] 

Other Information

ATC CodeN/A
Related LinksN/A