O6-Benzylguanine

N/A

Report date: 2025/11/22 20:00:09
NME

Base Information

Drug NameO6-Benzylguanine
Drug Alias Name苄基鸟嘌呤BenzylguanineAlkyladeNSC-638037O6-BG +[7] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of Action6-O-methylguanine-DNA methyltransferase inhibitors
Targets6-O-methylguanine-DNA methyltransferase
Therapy Area/IndicationsSkin MelanomaCNS Embryonal TumorSolid tumours +[35] 
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryCanadaUnited StatesAustralia
CombinationsNo
Global Highest StatusPhase 2 Clinical
Highest Status in ChinaN/A
Originator CompaniesNational Cancer Institute
China Registration ClassN/A

Develop Information

Active CompaniesNational Cancer Institute
Inactive CompaniesKeryx / Aoi Pharmaceuticals IncDuke UniversityThe University Of Chicago
Active IndicationsGliosarcomaGlioblastoma
Inactive IndicationsSkin MelanomaCNS Embryonal TumorSolid tumours +[33] 

Other Information

ATC CodeN/A
Related LinksWikipedia