PX-578

N/A

Report date: 2025/06/05 11:25:50
NMEFirst In Class

Base Information

Drug NamePX-578
Drug Alias NamePX-578POLG – SM
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionDNA Polymerase gamma activators
TargetsDNA Polymerase gamma
Therapy Area/IndicationsMitochondrial DNA Depletion SyndromeNerve DegenerationAlzheimer Disease +[4] 
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryUnited States
CombinationsNo
Global Highest StatusPhase 1 Clinical
Highest Status in ChinaN/A
Originator CompaniesPretzel Therapeutics Inc
China Registration ClassN/A

Develop Information

Active CompaniesPretzel Therapeutics Inc
Inactive CompaniesN/A
Active IndicationsMitochondrial DNA Depletion SyndromeNerve DegenerationAlzheimer Disease +[4] 
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksN/A