Esketamine Hydrochloride

盐酸艾司氯胺酮

Report date: 2026/05/09 20:00:18

Base Information

Drug NameEsketamine Hydrochloride
Drug Alias Name艾氯胺酮盐酸盐(S)-Ketamine hydrochlorideS(+)-ketamine盐酸艾司氯胺酮鼻用喷雾剂艾司氯胺酮 +[16] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionGlutamate [NMDA] receptor antagonists
TargetsGlutamate [NMDA] receptor
Therapy Area/IndicationsLiver DysfunctionStress Disorders, Post-TraumaticDepressive Disorder, Treatment-Resistant +[15] 
Global Approved IndicationsDepressive Disorder, Treatment-ResistantDepressive Disorder, MajorPain +[4] 
Approved Indications in ChinaAnesthesia
Original Approved Country/TerritoryGermany
Original Approved Date1997/08/01
Country/TerritoryCzechiaBelgiumBulgaria +[38] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesPfizer IncJohnson & Johnson Innovative MedicineAuris Medical
China Registration ClassN/A

Develop Information

Active CompaniesFederal University Of Sao PauloJanssen-Cilag International NvUT Health San Antonio +[9] 
Inactive CompaniesXian Janssen Pharmaceutical LtdAuris Medical IncMedical University Of Innsbruck +[8] 
Active IndicationsStress Disorders, Post-TraumaticDepressive Disorder, Treatment-ResistantDepressive Disorder, Major +[10] 
Inactive IndicationsLiver DysfunctionBipolar DisorderRenal Insufficiency +[5] 

Other Information

ATC CodeN01AX14N06AX27
Related LinksWikipediaKEGG