IMD-2146

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Report date: 2026/05/06 20:02:28

Base Information

Drug NameIMD-2146
Drug Alias Namedual-payload ADC EGFR-TROP2-TMEAlinker-RASi-DXd IMD2146IMD-2146IMD2146IMD 2146
ClassificationBiologics > Protein drugs > Immunoglobulin > Antibody > Antibody conjugate > Antibody drug conjugate (ADC)Biologics > Protein drugs > Immunoglobulin > Antibody > Monoclonal antibody > Multispecific monoclonal antibody > Bispecific monoclonal antibodyBiologics > Protein drugs > Immunoglobulin > Antibody > Antibody conjugate > Antibody drug conjugate (ADC) > Linker > Cleavable linker > Legumain-cleavable linker +[4] 
Mechanisms of ActionAnti-Epidermal growth factor receptor erbB1Anti-Trop-2GTPase Ras inhibitors +[4] 
TargetsEpidermal growth factor receptor erbB1Tumor-associated calcium signal transducer 2GTPase Ras +[4] 
Therapy Area/IndicationsNeoplasms
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryMainland China
CombinationsNo
Global Highest StatusPreclinical
Highest Status in ChinaPreclinical
Originator CompaniesShanghai Affinity Biopharmaceutical Co Ltd
China Registration ClassN/A

Develop Information

Active CompaniesShanghai Affinity Biopharmaceutical Co Ltd
Inactive CompaniesN/A
Active IndicationsNeoplasms
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksN/A