TROP2-targeted cytotoxic peptides and drug conjugates (Kyungpook National University)

N/A

Report date: 2026/04/17 20:02:02

NME

Base Information

Drug NameTROP2-targeted cytotoxic peptides and drug conjugates (Kyungpook National University)

Drug Alias Namecyclic form of TROP2-binding peptide linked with a pro-apoptotic D-form klaklakklaklak (kla) peptide or monomethyl auristatin E (MMAE) via a fatty acid linker (Kyungpook National University)

ClassificationSmall molecules > Synthetic peptide > Circular polypeptideSmall molecules > Synthetic peptide > Peptide drug conjugate (PDC)

Mechanisms of ActionTumor-associated calcium signal transducer 2 bindersTubulin inhibitors

TargetsTumor-associated calcium signal transducer 2Tubulin

Therapy Area/IndicationsTriple Negative Breast Neoplasms

Global Approved IndicationsN/A

Approved Indications in ChinaN/A

Original Approved Country/TerritoryN/A

Original Approved DateN/A

Country/TerritorySouth Korea

CombinationsNo

Global Highest StatusPreclinical

Highest Status in ChinaN/A

Originator CompaniesKyungpook National University

China Registration ClassN/A

Develop Information

Active CompaniesKyungpook National University

Inactive CompaniesN/A

Active IndicationsTriple Negative Breast Neoplasms

Inactive IndicationsN/A

Other Information

ATC CodeN/A