Fab-PE24 (Shanghai JiaoTong University)

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Report date: 2026/04/16 20:00:17

Base Information

Drug NameFab-PE24 (Shanghai JiaoTong University)
Drug Alias NameFab-PE24——conjugating the Fab fragment of a humanized anti-TROP2 monoclonal antibody with a truncated Pseudomonas aeruginosa exotoxin A (PE24KDEL) using SpyCatcher-SpyTag technology人源化抗TROP2单克隆抗体的Fab片段与截短的铜绿假单胞菌外毒素A (PE24KDEL) 偶联的免疫毒素Fab-PE24
ClassificationBiologics > Protein drugs > Immunoglobulin > Antibody > Antibody conjugate > Antibody drug conjugate (ADC)Biologics > Protein drugs > Immunoglobulin > Antibody > Monoclonal antibody > Monoclonal antibody humanized
Mechanisms of ActionAnti-Trop-2
TargetsTumor-associated calcium signal transducer 2
Therapy Area/IndicationsNeoplasms
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryMainland China
CombinationsNo
Global Highest StatusPreclinical
Highest Status in ChinaPreclinical
Originator CompaniesShanghai Jiaotong University
China Registration ClassN/A

Develop Information

Active CompaniesShanghai Jiaotong University
Inactive CompaniesN/A
Active IndicationsNeoplasms
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksN/A