MDEG-541

N/A

Report date: 2023/03/07 15:25:37

NME

Base Information

Drug NameMDEG-541

Drug Alias NameMDEG-541

ClassificationSmall molecules > Proteolysis-Targeting Chimera (PROTAC)

Mechanisms of ActionPolo like kinase 1 degradersEukaryotic peptide chain release factor GTP-binding subunit ERF3B degradersEukaryotic peptide chain release factor GTP-binding subunit ERF3A degraders

TargetsPolo like kinase 1Eukaryotic peptide chain release factor GTP-binding subunit ERF3AEukaryotic peptide chain release factor GTP-binding subunit ERF3B

Therapy Area/IndicationsGastrointestinal Neoplasms

Global Approved IndicationsN/A

Approved Indications in ChinaN/A

Original Approved Country/TerritoryN/A

Original Approved DateN/A

Country/TerritoryGermany

CombinationsNo

Global Highest StatusPreclinical

Highest Status in ChinaN/A

Originator CompaniesKlinikum Rechst Der Isar Technische Universitaet Muenchen

China Registration ClassN/A

Develop Information

Active CompaniesKlinikum Rechst Der Isar Technische Universitaet Muenchen

Inactive CompaniesN/A

Active IndicationsGastrointestinal Neoplasms

Inactive IndicationsN/A

Other Information

ATC CodeN/A