TH-9619

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Report date: 2025/09/03 20:01:14

Base Information

Drug NameTH-9619
Drug Alias NameTH-9619
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial inhibitors
TargetsBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
Therapy Area/IndicationsSolid tumoursGastrointestinal DiseasesCarcinoma, Non-Small-Cell Lung +[7] 
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritorySwedenUnited KingdomFrance +[4] 
CombinationsNo
Global Highest StatusPhase 2 Clinical
Highest Status in ChinaN/A
Originator CompaniesKarolinska Institutet
China Registration ClassN/A

Develop Information

Active CompaniesOne-carbon Therapeutics ABKarolinska Institutet
Inactive CompaniesN/A
Active IndicationsSolid tumoursGastrointestinal DiseasesCarcinoma, Non-Small-Cell Lung +[7] 
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksN/A