Alteplase

阿替普酶

Report date: 2026/03/26 20:00:17

Base Information

Drug NameAlteplase
Drug Alias NameTissue plasminogen activator阿特普酶t-PA (Genentech)Recombinant tissue plasminogen activatorAlteplasa +[21] 
ClassificationBiologics > Protein drugs > Enzyme > Recombinant enzymeBiologics > Protein drugs > Recombinant protein > Recombinant enzyme
Mechanisms of ActionPlasminogen stimulants
TargetsPlasminogen
Therapy Area/IndicationsIschemic StrokePostphlebitic SyndromePostthrombotic Syndrome +[28] 
Global Approved IndicationsMyocardial InfarctionStrokeBrain Ischemia +[4] 
Approved Indications in ChinaMyocardial InfarctionStrokePulmonary Embolism
Original Approved Country/TerritoryUnited States
Original Approved Date1987/11/13
Country/TerritoryCzechiaBelgiumCanada +[34] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesGenentech Inc
China Registration ClassN/A

Develop Information

Active CompaniesC.H. Boehringer Sohn Ag & Co. KgChinese University Of Hong Kong (Cuhk)Boehringer Ingelheim Pharma Gmbh & Co Kg +[6] 
Inactive CompaniesNational Institutes Of Health Clinical Center (Cc)National Institute For Health Research, United KingdomThe Florey Institute Of Neuroscience And Mental Health +[26] 
Active IndicationsMyocardial InfarctionStrokeBrain Ischemia +[8] 
Inactive IndicationsIschemic StrokePostphlebitic SyndromePostthrombotic Syndrome +[20] 

Other Information

ATC CodeB01AD02S01XA13
Related LinksWikipediaDrugBankKEGG