Tapentadol Hydrochloride

盐酸他喷他多

Report date: 2026/04/06 20:01:48
NME

Base Information

Drug NameTapentadol Hydrochloride
Drug Alias Name他喷他多tapentadolumNucynta ERPalexia retardPalexia SR +[19] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionNorepinephrine transporter inhibitorsMu opioid receptor agonists
TargetsNorepinephrine transporterMu opioid receptor
Therapy Area/IndicationsDiabetic peripheral neuropathyNociceptive PainChronic Pain +[25] 
Global Approved IndicationsAcute PainPain
Approved Indications in ChinaAcute Pain
Original Approved Country/TerritoryUnited States
Original Approved Date2008/11/20
Country/TerritoryCzechiaBelgiumBulgaria +[35] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesJohnson & Johnson Innovative MedicineJohnson & Johnson
China Registration ClassN/A

Develop Information

Active CompaniesJohnson & Johnson Innovative MedicineYichang Humanwell Pharmaceutical Co LtdCollegium Pharmaceutical Inc +[5] 
Inactive CompaniesJanssen-Cilag International NvGrünenthal GmbHOrtho-Mcneil Janssen Scientific Affairs Llc +[6] 
Active IndicationsDiabetic peripheral neuropathyChronic PainCancer Pain +[8] 
Inactive IndicationsNociceptive PainLow Back PainBack Pain +[17] 

Other Information

ATC CodeN02AX06
Related LinksWikipediaDrugBankKEGG