Ademetionine 1,4-Butanedisulfonate

丁二磺酸腺苷蛋氨酸

Report date: 2026/05/13 20:02:10
NME

Base Information

Drug NameAdemetionine 1,4-Butanedisulfonate
Drug Alias Name腺苷甲硫氨酸ademetioninaAdoMetStradaademetioninum +[25] 
ClassificationSmall molecules
Mechanisms of ActionPhosphodiesterase 4B inhibitors
TargetsPhosphodiesterase 4B
Therapy Area/IndicationsDepressive Disorder, MajorDepressionCardiomyopathy, Hypertrophic, Familial +[11] 
Global Approved IndicationsLiver Cirrhosis, BiliaryCholestasis
Approved Indications in ChinaLiver Cirrhosis, Biliary
Original Approved Country/TerritoryItaly
Original Approved Date1975/01/01
Country/TerritoryUnited StatesRussian FederationItaly +[5] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesAbbott Laboratories
China Registration ClassN/A

Develop Information

Active CompaniesAbbott LaboratoriesCedars-Sinai Medical CenterNational Center For Cardiovascular Diseases, China +[4] 
Inactive CompaniesThe University Of California DavisDeakin UniversityMsi Methylation Sciences Inc +[7] 
Active IndicationsCardiomyopathy, Hypertrophic, FamilialMetabolic Dysfunction-Associated Steatotic Liver DiseaseLiver Cirrhosis, Biliary +[4] 
Inactive IndicationsDepressive Disorder, MajorDepressionLiver Diseases, Alcoholic +[7] 

Other Information

ATC CodeA16AA02
Related LinksWikipediaKEGG