Dual PD-L1 Checkpoint Inhibitor/CD28 Costimulator (Xencor)

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Report date: 2026/03/19 16:59:29

Base Information

Drug NameDual PD-L1 Checkpoint Inhibitor/CD28 Costimulator (Xencor)

Drug Alias NamePD-L1/CD28 monoclonal antibody (Xencor)PD-L1/CD28 Bispecific Antibody (Xencor)

ClassificationBiologics > Protein drugs > Immunoglobulin > Antibody > Monoclonal antibody > Multispecific monoclonal antibody > Bispecific monoclonal antibodyBiologics > T cell engagers

Mechanisms of ActionT-cell-specific surface glycoprotein CD28 agonistsProgrammed death-ligand 1 blockers

TargetsT-cell-specific surface glycoprotein CD28Programmed death-ligand 1

Therapy Area/IndicationsSolid tumours

Global Approved IndicationsN/A

Approved Indications in ChinaN/A

Original Approved Country/TerritoryN/A

Original Approved DateN/A

Country/TerritoryUnited States

CombinationsNo

Global Highest StatusPreclinical

Highest Status in ChinaN/A

Originator CompaniesXencor Inc

China Registration ClassN/A

Develop Information

Active CompaniesXencor Inc

Inactive CompaniesN/A

Active IndicationsSolid tumours

Inactive IndicationsN/A

Other Information

ATC CodeN/A