Dual 4-1BB Costimulator/Anti-EphA2 (MacroGenics)

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Report date: 2026/02/06 17:42:18

Base Information

Drug NameDual 4-1BB Costimulator/Anti-EphA2 (MacroGenics)

Drug Alias NameEphA2 x CD137 bispecific DART (MacroGenics)

ClassificationBiologics > Protein drugs > Immunoglobulin > Antibody > Monoclonal antibody > Multispecific monoclonal antibody > Bispecific monoclonal antibody

Mechanisms of ActionEphrin type-A receptor 2 modulatorsTumor necrosis factor receptor superfamily member 9 stimulants

TargetsEphrin type-A receptor 2Tumor necrosis factor receptor superfamily member 9

Therapy Area/IndicationsNeoplasms

Global Approved IndicationsN/A

Approved Indications in ChinaN/A

Original Approved Country/TerritoryN/A

Original Approved DateN/A

Country/TerritoryUnited States

CombinationsNo

Global Highest StatusPending (Preclinical)

Highest Status in ChinaN/A

Originator CompaniesMacrogenics Inc

China Registration ClassN/A

Develop Information

Active CompaniesN/A

Inactive CompaniesMacrogenics Inc

Active IndicationsN/A

Inactive IndicationsNeoplasms

Other Information

ATC CodeN/A