anti-CD3/anti-5T4 T-cell engager DART (MacroGenics)

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Report date: 2026/03/19 16:58:32

Base Information

Drug Nameanti-CD3/anti-5T4 T-cell engager DART (MacroGenics)

Drug Alias Name5T4 x CD3 bispecific DART (MacroGenics)

ClassificationBiologics > Protein drugs > Immunoglobulin > Antibody > Monoclonal antibody > Multispecific monoclonal antibody > Bispecific monoclonal antibodyBiologics > T cell engagers

Mechanisms of ActionTrophoblast glycoprotein modulatorsT cell surface glycoprotein CD3 modulators

TargetsTrophoblast glycoproteinT cell surface glycoprotein CD3

Therapy Area/IndicationsNeoplasms

Global Approved IndicationsN/A

Approved Indications in ChinaN/A

Original Approved Country/TerritoryN/A

Original Approved DateN/A

Country/TerritoryUnited States

CombinationsNo

Global Highest StatusPreclinical

Highest Status in ChinaN/A

Originator CompaniesMacrogenics Inc

China Registration ClassN/A

Develop Information

Active CompaniesMacrogenics Inc

Inactive CompaniesN/A

Active IndicationsNeoplasms

Inactive IndicationsN/A

Other Information

ATC CodeN/A