AG-1031

N/A

Report date: 2025/01/26 19:09:07

NME

Base Information

Drug NameAG-1031

Drug Alias NamePC4/VEGF inhibitor (AscentGene)SIRT1/p53 inhibitor (AscentGene)AG-1031

ClassificationSmall molecules > Heterocyclic drugs

Mechanisms of ActionNAD-dependent deacetylase sirtuin 1 inhibitorsNeurogenic locus notch homolog protein 1 inhibitorsTumor protein p53 inhibitors +[4]

TargetsNAD-dependent deacetylase sirtuin 1Tumor protein p53Neurogenic locus notch homolog protein 1 +[4]

Therapy Area/IndicationsNeuroblastomaGlioma

Global Approved IndicationsN/A

Approved Indications in ChinaN/A

Original Approved Country/TerritoryN/A

Original Approved DateN/A

Country/TerritoryUnited States

CombinationsNo

Global Highest StatusPreclinical

Highest Status in ChinaN/A

Originator CompaniesAscentgene Inc

China Registration ClassN/A

Develop Information

Active CompaniesAscentgene Inc

Inactive CompaniesN/A

Active IndicationsNeuroblastomaGlioma

Inactive IndicationsN/A

Other Information

ATC CodeN/A