MGAP-9

N/A

Report date: 2025/01/26 16:25:38

NME

Base Information

Drug NameMGAP-9

Drug Alias Nameapurinic/apyrimidinic endonuclease 1/O6-methylguanine-DNA-methyltransferase inhibitor (Texas Tech University Health Sciences Center)APE-1/MGMT dual inhibitor (Texas Tech University Health Sciences Center)MGAP-9

ClassificationSmall molecules > Heterocyclic drugs

Mechanisms of ActionDNA-(apurinic or apyrimidinic site) lyase inhibitors6-O-methylguanine-DNA methyltransferase inhibitors

TargetsDNA-(apurinic or apyrimidinic site) lyase6-O-methylguanine-DNA methyltransferase

Therapy Area/IndicationsGlioblastoma

Global Approved IndicationsN/A

Approved Indications in ChinaN/A

Original Approved Country/TerritoryN/A

Original Approved DateN/A

Country/TerritoryUnited States

CombinationsNo

Global Highest StatusPreclinical

Highest Status in ChinaN/A

Originator CompaniesTexas Tech University

China Registration ClassN/A

Develop Information

Active CompaniesTexas Tech University

Inactive CompaniesN/A

Active IndicationsGlioblastoma

Inactive IndicationsN/A

Other Information

ATC CodeN/A