TEAD4-YAP protein-protein interaction inhibitor (Universitat Dortmund/Lead Discovery Center/Max Planck Institute of Molecular Physiology/AstraZeneca/University of Groningen/University of Crete)

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Report date: 2025/01/26 17:26:39
NME

Base Information

Drug NameTEAD4-YAP protein-protein interaction inhibitor (Universitat Dortmund/Lead Discovery Center/Max Planck Institute of Molecular Physiology/AstraZeneca/University of Groningen/University of Crete)
Drug Alias Nametranscriptional enhanced associate domain 4-Yes-associated protein interaction inhibitor (Universitat Dortmund/Lead Discovery Center/Max Planck Institute of Molecular Physiology/AstraZeneca/University of Groningen/University of Crete)VK-57
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionTranscriptional coactivator YAP1 modulatorsTranscriptional enhancer factor TEF-4 modulators
TargetsTranscriptional enhancer factor TEF-4Transcriptional coactivator YAP1
Therapy Area/IndicationsNeoplasms
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritorySwedenNetherlandsGermany
CombinationsNo
Global Highest StatusPreclinical
Highest Status in ChinaN/A
Originator CompaniesTu Dortmund University
China Registration ClassN/A

Develop Information

Active CompaniesTu Dortmund UniversityRijksuniversiteit te GroningenLead Discovery Center GmbH +[6] 
Inactive CompaniesN/A
Active IndicationsNeoplasms
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksN/A