TROP2 ProTriTAC (Harpoon Therapeutics)

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Report date: 2026/04/15 20:02:38

Base Information

Drug NameTROP2 ProTriTAC (Harpoon Therapeutics)
Drug Alias NameTROP2 protease-activated trispecific T-cell engager prodrug (ProTriTAC) (Harpoon Therapeutics)
ClassificationBiologics > T cell engagersBiologics > Protein drugs > Immunoglobulin > Antibody > Monoclonal antibody > Multispecific monoclonal antibody > Trispecific monoclonal antibody
Mechanisms of ActionTumor-associated calcium signal transducer 2 modulatorsT cell surface glycoprotein CD3 modulatorsAnti-Albumins
TargetsTumor-associated calcium signal transducer 2T cell surface glycoprotein CD3Albumins
Therapy Area/IndicationsSolid tumoursHead and Neck NeoplasmsPancreatic Neoplasms +[4] 
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryUnited States
CombinationsNo
Global Highest StatusPreclinical
Highest Status in ChinaN/A
Originator CompaniesHarpoon Therapeutics Inc
China Registration ClassN/A

Develop Information

Active CompaniesHarpoon Therapeutics IncMerck & Co Inc
Inactive CompaniesN/A
Active IndicationsSolid tumoursHead and Neck NeoplasmsPancreatic Neoplasms +[4] 
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksN/A