NF-kappaB/IKK inhibitors (Nereus)

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Report date: 2025/06/11 20:01:15
NME

Base Information

Drug NameNF-kappaB/IKK inhibitors (Nereus)
Drug Alias NameNF-kB activation inhibitors (Nereus)apoptosis stimulators (Nereus)salinosporamide Bnuclear factor-kappaB activation inhibitors (Nereus)NPI-1342 +[15] 
ClassificationSmall molecules
Mechanisms of ActionCaspase-9 activatorsAnticancer protein kinase inhibitorsApoptosis stimulants +[6] 
TargetsNuclear factor NF-kappa-B complexCaspase-9Inhibitor of NF-kappa-B kinase (IKK) +[4] 
Therapy Area/IndicationsInflammationNeoplasms
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryUnited States
CombinationsNo
Global Highest StatusPending (Preclinical)
Highest Status in ChinaN/A
Originator CompaniesNereus Pharmaceuticals Inc
China Registration ClassN/A

Develop Information

Active CompaniesN/A
Inactive CompaniesNereus Pharmaceuticals Inc
Active IndicationsN/A
Inactive IndicationsInflammationNeoplasms

Other Information

ATC CodeN/A
Related LinksN/A