Disulfiram

双硫仑

Report date: 2026/05/06 20:02:28
NME

Base Information

Drug NameDisulfiram
Drug Alias NameDisulfirame戒酒硫双硫醒Disulfiramum二硫化四乙基秋兰姆 +[10] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionAlcohol dehydrogenases inhibitors
TargetsAlcohol dehydrogenases
Therapy Area/IndicationsCoronavirus Disease 2019 (COVID-19)Metastatic breast cancerCocaine-Related Disorders +[22] 
Global Approved IndicationsAlcoholismAlcoholic Intoxication
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date1951/08/28
Country/TerritoryCzechiaUnited StatesSlovakia +[6] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesTeva
China Registration ClassN/A

Develop Information

Active CompaniesUniversity Of RochesterThe University Of OklahomaNational Cancer Institute-Slovakia +[7] 
Inactive CompaniesUtah State UniversityUniversity Of California San FranciscoYale University +[8] 
Active IndicationsMetastatic breast cancerAlcoholic IntoxicationFatigue +[13] 
Inactive IndicationsCoronavirus Disease 2019 (COVID-19)Cocaine-Related DisordersAlcoholism +[9] 

Other Information

ATC CodeN07BB01P03AA04
Related LinksWikipediaDrugBankKEGG