Difelikefalin acetate

醋酸地非法林

Report date: 2026/05/13 20:02:10
NMEFirst In Class

Base Information

Drug NameDifelikefalin acetate
Drug Alias NameDifelikefalinum地克法林DifelicefalinaDifelikefalinKORSUVA +[11] 
ClassificationSmall molecules > Synthetic peptide
Mechanisms of ActionKappa opioid receptor agonists
TargetsKappa opioid receptor
Therapy Area/IndicationsAcute PainPainPain, Postoperative +[14] 
Global Approved IndicationsPruritus
Approved Indications in ChinaPruritus
Original Approved Country/TerritoryUnited States
Original Approved Date2021/08/23
Country/TerritoryCzechiaBulgariaCanada +[26] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesFerring Bv
China Registration ClassN/A

Develop Information

Active CompaniesVifor Fresenius Medical Care Renal Pharma LtdSiegfried Hameln GmbhVifor Inc +[9] 
Inactive CompaniesCara Therapeutics IncQilu Pharmaceutical(Hainan) Co LtdKissei Pharmaceutical Co Ltd
Active IndicationsPruritusKidney Failure, ChronicRenal Insufficiency, Chronic
Inactive IndicationsAcute PainPainPain, Postoperative +[11] 

Other Information

ATC CodeN/A
Related LinksWikipediaDrugBankKEGG