Apadamtase alfa/Cinaxadamtase alfa

阿帕达酶α/辛奈达酶α

Report date: 2026/04/21 20:00:18

Base Information

Drug NameApadamtase alfa/Cinaxadamtase alfa
Drug Alias NameRecombinant-A disintegrin and mellatoproteinase with thrombospondin type-1 motifs-13Recombinant ADAMTS13recombinant-krhnrADAMTS13 Q23/rADAMTS13 R23ADZYNMA +[11] 
ClassificationBiologics > Protein drugs > Recombinant protein > Recombinant coagulation factorBiologics > Protein drugs > Recombinant proteinBiologics > Protein drugs > Enzyme
Mechanisms of ActionA disintegrin and metalloproteinase with thrombospondin motifs 13 replacement
TargetsA disintegrin and metalloproteinase with thrombospondin motifs 13
Therapy Area/IndicationsIschemic StrokePurpura, Thrombotic ThrombocytopenicPurpura, Thrombocytopenic +[4] 
Global Approved IndicationsPurpura, Thrombotic Thrombocytopenic
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date2023/11/09
Country/TerritoryBelgiumCanadaUnited States +[17] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaNDA/BLA
Originator CompaniesKM Biologics Co Ltd
China Registration ClassN/A

Develop Information

Active CompaniesTakeda (China) International Trading Co LtdShireOrsini Specialty Pharmacy Inc +[12] 
Inactive CompaniesN/A
Active IndicationsIschemic StrokePurpura, Thrombotic ThrombocytopenicPurpura, Thrombocytopenic +[4] 
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksWikipediaDrugBankKEGG