Tigecycline

替加环素

Report date: 2026/03/04 20:01:44
NME

Base Information

Drug NameTigecycline
Drug Alias Nametigeciclina替吉环素老虎环素Tigecyclinum老虎霉素 +[12] 
ClassificationSmall molecules > Heterocyclic drugs > Antibiotics > Tetracycline antibiotics
Mechanisms of ActionMitochondrial proteins inhibitors30S ribosomal subunit inhibitors
TargetsMitochondrial proteins30S ribosomal subunit
Therapy Area/IndicationsComplicated Skin and Soft Tissue InfectionsCommunity Acquired PneumoniaHelicobacter pylori infection +[22] 
Global Approved IndicationsComplicated Skin and Soft Tissue InfectionsCommunity-acquired bacterial pneumoniaPneumonia +[7] 
Approved Indications in ChinaComplicated Skin and Soft Tissue InfectionsCommunity-acquired bacterial pneumoniaIntraabdominal Infections +[5] 
Original Approved Country/TerritoryUnited States
Original Approved Date2005/06/15
Country/TerritoryBelgiumCanadaUnited States +[24] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesPfizer Inc
China Registration ClassN/A

Develop Information

Active CompaniesWyeth Pharmaceuticals IncPfizer IncPf Prism Cv +[5] 
Inactive CompaniesWyeth LlcAccord Healthcare IncUniversity Of California San Diego +[4] 
Active IndicationsComplicated Skin and Soft Tissue InfectionsHelicobacter pylori infectionCommunity-acquired bacterial pneumonia +[8] 
Inactive IndicationsCommunity Acquired PneumoniaSkin DiseasesKidney Failure, Chronic +[14] 

Other Information

ATC CodeJ01AA12
Related LinksWikipediaDrugBankKEGG