Ivabradine Hydrochloride

盐酸伊伐布雷定

Report date: 2026/05/26 20:00:28
NMEFirst In Class

Base Information

Drug NameIvabradine Hydrochloride
Drug Alias Name盐酸依伐布雷定盐酸伊伐雷定伊伐布雷定ProcoralanCorlentor +[13] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionHyperpolarization-activated cyclic nucleotide-gated channel blockers
TargetsHyperpolarization-activated cyclic nucleotide-gated channel
Therapy Area/IndicationsVentricular Dysfunction, LeftCoronary DiseaseAngina, Stable +[9] 
Global Approved IndicationsAngina PectorisHeart Failure
Approved Indications in ChinaAngina Pectoris
Original Approved Country/TerritoryEU
Original Approved Date2005/10/25
Country/TerritoryCanadaUnited StatesPoland +[9] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesLes Laboratoires Servier
China Registration ClassN/A

Develop Information

Active CompaniesJagiellonian University Sylff Fellows AssociationOno Pharmaceutical Co LtdLes Laboratoires Servier +[7] 
Inactive CompaniesDana-Farber Cancer InstituteUniversity of Sao PauloInstitut De Recherches Internationales Servier +[4] 
Active IndicationsAngina, StableAngina PectorisMyocardial Ischemia +[4] 
Inactive IndicationsVentricular Dysfunction, LeftCoronary DiseaseAutonomic Nervous System Diseases +[5] 

Other Information

ATC CodeC01EB17
Related LinksWikipediaDrugBankKEGG