Arsenic Trioxide

三氧化二砷

Report date: 2026/04/16 20:00:17
NME

Base Information

Drug NameArsenic Trioxide
Drug Alias Name白砷White Arsenic二氧化二砷三氧化砷Arsenic SesquioxideArsenic (III) Oxide +[12] 
ClassificationSmall molecules
Mechanisms of ActionImmunostimulantsThioredoxin reductase inhibitorsDNA synthesis inhibitors +[4] 
TargetsThioredoxin reductase
Therapy Area/IndicationsEsophageal adenocarcinomaCNS Embryonal TumorSolid tumours +[50] 
Global Approved IndicationsLiver NeoplasmsLeukemia, Promyelocytic, Acute
Approved Indications in ChinaLiver NeoplasmsLeukemia, Promyelocytic, Acute
Original Approved Country/TerritoryUnited States
Original Approved Date2000/09/25
Country/TerritoryCanadaUnited StatesPuerto Rico +[8] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesTeva
China Registration ClassN/A

Develop Information

Active CompaniesBeijing Sl Pharmaceutical Co LtdTeva BvNational Cancer Institute +[7] 
Inactive CompaniesUT Health San AntonioWake Forest University Health SciencesWashington University School Of Medicine +[23] 
Active IndicationsLiver NeoplasmsPheochromocytomaNeuroblastoma +[5] 
Inactive IndicationsEsophageal adenocarcinomaCNS Embryonal TumorSolid tumours +[45] 

Other Information

ATC CodeL01XX27
Related LinksWikipediaDrugBankKEGG