Zoledronic Acid Hydrate

唑来膦酸

Report date: 2026/03/20 20:03:07
NME

Base Information

Drug NameZoledronic Acid Hydrate
Drug Alias NameZoledronateacidum zoledronicumZoledronic Acidnanoparticles containing Zoledronic acidZoredronic acid +[20] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionFarnesyl diphosphate synthase inhibitorsBone resorption factor inhibitors
TargetsBone resorption factorFarnesyl diphosphate synthase
Therapy Area/IndicationsBone metastasesGlucocorticoid-induced osteoporosisBone marrow transplant rejection +[83] 
Global Approved IndicationsFractures, BoneHypercalcemiaOsteitis Deformans +[7] 
Approved Indications in ChinaHypercalcemia
Original Approved Country/TerritoryCanada
Original Approved Date2000/01/01
Country/TerritoryCzechiaBelgiumCanada +[50] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesNovartis Pharma Ag
China Registration ClassN/A

Develop Information

Active CompaniesSandozInstitute Of Hematology & Blood Diseases HospitalSandoz Pharmaceuticals Dd +[15] 
Inactive CompaniesDana-Farber Cancer InstituteUniversity Of California San FranciscoHamad Medical Corporation +[46] 
Active IndicationsBone metastasesGlucocorticoid-induced osteoporosisRotator Cuff Injuries +[37] 
Inactive IndicationsBone marrow transplant rejectionMetastatic breast cancerHormone-Resistant Prostate Neoplasms +[46] 

Other Information

ATC CodeM05BA08
Related LinksWikipediaDrugBankKEGG