Asparaginase (Recombinant)

重组天冬酰胺酶

Report date: 2026/03/31 20:00:21

Base Information

Drug NameAsparaginase (Recombinant)
Drug Alias NameKidrolase重组天门冬酰胺酶重组L-门冬酰胺酶Colaspase (BAN)L-Asparaginase (JAN) +[10] 
ClassificationBiologics > Protein drugs > Enzyme > Recombinant enzymeBiologics > Protein drugs > Recombinant protein > Recombinant enzyme
Mechanisms of ActionAspartate-ammonia ligase inhibitorsAmidohydrolases stimulantsAsparagine inhibitors
TargetsAspartate-ammonia ligaseAmidohydrolasesAsparagine
Therapy Area/IndicationsNeutropeniaMyelodysplastic SyndromesMyelodysplastic-Myeloproliferative Diseases +[29] 
Global Approved IndicationsPrecursor Cell Lymphoblastic Leukemia-Lymphoma
Approved Indications in ChinaN/A
Original Approved Country/TerritoryEU
Original Approved Date2016/01/14
Country/TerritoryCanadaUnited StatesPuerto Rico +[13] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaPending
Originator CompaniesMedac
China Registration ClassN/A

Develop Information

Active CompaniesMedac Gesellschaft Fur Klinische Spezialpraeparate GmbhNational Cancer Institute
Inactive CompaniesDana-Farber Cancer InstituteNational Institutes Of Health Clinical Center (Cc)Hannover Medical School +[5] 
Active IndicationsMyelodysplastic SyndromesBone Marrow NeoplasmsSarcoma, Myeloid +[14] 
Inactive IndicationsNeutropeniaMyelodysplastic-Myeloproliferative DiseasesThrombocytopenia +[15] 

Other Information

ATC CodeL01XX02
Related LinksWikipediaDrugBankKEGG