Interferon gamma-1b

干扰素γ-1b

Report date: 2024/09/06 11:46:51

Base Information

Drug NameInterferon gamma-1b
Drug Alias NameIFN-gamma-1bIFNγ-1bImukin 1ActimmuneImmukin +[8] 
ClassificationBiologics > Protein drugs > Recombinant protein > Recombinant cytokines
Mechanisms of ActionInterferon gamma receptor stimulantsAntibody-dependent cell-mediated cytotoxicity (ADCC) effectsImmunostimulants
TargetsInterferon gamma receptor
Therapy Area/IndicationsPlaque psoriasisGranulomatous Disease, ChronicMyelodysplastic Syndromes +[29] 
Global Approved IndicationsGranulomatous Disease, ChronicOsteopetrosis
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date1999/02/25
Country/TerritoryUnited StatesRomaniaNetherlands +[7] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesGenentech Inc
China Registration ClassN/A

Develop Information

Active CompaniesHorizon Therapeutics Ireland DacRadboud University Medical CenterManchester University Nhs Foundation Trust +[4] 
Inactive CompaniesIntermune IncIndiana UniversityNational Cancer Institute +[10] 
Active IndicationsGranulomatous Disease, ChronicMyelodysplastic SyndromesOsteopetrosis +[7] 
Inactive IndicationsPlaque psoriasisUveitis, AnteriorUveitis +[22] 

Other Information

ATC CodeL03AB03
Related LinksDrugBankKEGG