Imetelstat

N/A

Report date: 2025/09/12 13:39:38
NME

Base Information

Drug NameImetelstat
Drug Alias NameImetelstatum艾泰司他Imetelstat sodium伊美司他RYTELO +[12] 
ClassificationSmall molecules > Nucleosides and nucleotide derivtives > Oligonucleotide > Oligonucleotide antisense
Mechanisms of ActionTelomerase reverse transcriptase inhibitors
TargetsTelomerase reverse transcriptase
Therapy Area/IndicationsMetastatic breast cancerCNS Embryonal TumorSolid tumours +[30] 
Global Approved IndicationsMyelodysplastic SyndromesAnemia
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date2024/06/06
Country/TerritoryCzechiaBelgiumBulgaria +[31] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesGeron Co
China Registration ClassN/A

Develop Information

Active CompaniesGeron CoGCP-Service International West GmbHGeron +[4] 
Inactive CompaniesIndiana UniversityNational Cancer Institute
Active IndicationsPrimary MyelofibrosisMyelodysplastic SyndromesAnemia +[4] 
Inactive IndicationsMetastatic breast cancerCNS Embryonal TumorSolid tumours +[26] 

Other Information

ATC CodeL01XX80
Related LinksWikipediaDrugBankKEGG