Amiloride Hydrochloride/Hydrochlorothiazide

盐酸阿米洛利/氢氯噻嗪

Report date: 2022/02/14 09:57:11

Base Information

Drug NameAmiloride Hydrochloride/Hydrochlorothiazide

Drug Alias NameAmiloride hydrochloride and hydrochlorothiazideHydrochlorothiazide/Amiloride HydrochlorideAmiloride hydrochloride - hydrochlorothiazide mixtModuretic 5-50GSK-3542503

ClassificationSmall molecules

Mechanisms of ActionThiazide-sensitive sodium-chloride cotransporter inhibitors

TargetsThiazide-sensitive sodium-chloride cotransporterSodium channel alpha subunit

Therapy Area/IndicationsHypertensionHeart FailureCystic Fibrosis

Global Approved IndicationsHypertensionHeart Failure

Approved Indications in ChinaN/A

Original Approved Country/TerritoryUnited States

Original Approved Date1981/10/05

Country/TerritoryUnited StatesSouth Africa

CombinationsYes Hydrochlorothiazide Amiloride Hydrochloride

Global Highest StatusWithdrawn

Highest Status in ChinaN/A

Originator CompaniesMerck & Co Inc

China Registration ClassN/A

Develop Information

Active CompaniesN/A

Inactive CompaniesGlaxosmithkline Plc Merck & Co Inc University Of North Carolina At Chapel Hill

Active IndicationsN/A

Inactive IndicationsHypertensionHeart FailureCystic Fibrosis

Other Information

ATC CodeC03EA01