Pyrimethamine/Sulfadoxine

乙胺嘧啶/磺胺多辛

Report date: 2023/04/25 11:29:38

Base Information

Drug NamePyrimethamine/Sulfadoxine
Drug Alias NameSulfadoxine/pyrimethamine磺胺多辛/乙胺嘧啶磺胺多辛+乙胺嘧啶sulfadoxime and pyrimethaminePyrimethamine - sulfadoxine +[9] 
ClassificationSmall molecules
Mechanisms of ActionFolate inhibitorsDihydrofolate reductase inhibitors
TargetsFolateDihydrofolate reductase
Therapy Area/IndicationsFastingAnemia, Sickle CellAnemia +[6] 
Global Approved IndicationsMalariaBacterial Infections
Approved Indications in ChinaBacterial Infections
Original Approved Country/TerritoryUnited States
Original Approved Date1981/10/28
Country/TerritoryZambiaUnited StatesUganda +[8] 
CombinationsYes SulfadoxinePyrimethamine
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesF. Hoffmann-La Roche Ltd
China Registration ClassN/A

Develop Information

Active CompaniesSwiss Pharma Nigeria LtdLondon School Of Hygiene And Tropical MedicineGuilin Pharmaceutical Co Ltd
Inactive CompaniesUniversity Of California San FranciscoSwiss Tropical & Public Health InstituteF. Hoffmann-La Roche Ltd +[5] 
Active IndicationsFastingMalariaBacterial Infections
Inactive IndicationsAnemia, Sickle CellAnemiaMalaria, Falciparum

Other Information

ATC CodeP01BD51
Related LinksKEGG