Dornase alfa

N/A

Report date: 2026/03/09 20:02:04

Base Information

Drug NameDornase alfa
Drug Alias NameDornase α阿法链道酶rhDNaseRecombinant human deoxyribonuclease IAERx-Dornase alfa +[12] 
ClassificationBiologics > Protein drugs > Enzyme > Recombinant enzymeBiologics > Protein drugs > Recombinant protein > Recombinant enzyme
Mechanisms of ActionDeoxyribonuclease 1 repalcementsDNA inhibitors
TargetsDNA
Therapy Area/IndicationsCoronavirus Disease 2019 (COVID-19)Ischemic StrokeHypoxia +[12] 
Global Approved IndicationsCystic Fibrosis
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date1993/12/30
Country/TerritoryCanadaUnited StatesTurkey +[8] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesGenentech Inc
China Registration ClassN/A

Develop Information

Active CompaniesLudwig Maximilians University Of MunichChugai Pharmaceutical Co LtdUniversity College London +[9] 
Inactive CompaniesUniversity Of MissouriUniversity Of VermontNorthwell Health, Inc +[7] 
Active IndicationsCoronavirus Disease 2019 (COVID-19)Ischemic StrokeHypoxia +[5] 
Inactive IndicationsXerophthalmiaEye DiseasesRespiratory Distress Syndrome, Adult +[7] 

Other Information

ATC CodeR05CB13
Related LinksWikipediaDrugBankKEGG