Tropifexor

N/A

Report date: 2026/05/20 20:02:01
NME

Base Information

Drug NameTropifexor
Drug Alias NameLJN-452
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionBile acid receptor FXR agonists
TargetsBile acid receptor FXR
Therapy Area/IndicationsMetabolic Dysfunction-Associated Steatotic Liver DiseaseLiver DiseasesCholangitis, Sclerosing
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryBelgiumBulgariaCanada +[32] 
CombinationsNo
Global Highest StatusDiscontinued (Phase 2 Clinical)
Highest Status in ChinaDiscontinued
Originator CompaniesNovartis Pharma Ag
China Registration ClassN/A

Develop Information

Active CompaniesN/A
Inactive CompaniesNovartis Pharma AgAptuit (Verona) SrlChina Novartis Institutes For Biomedical Research Co Ltd
Active IndicationsN/A
Inactive IndicationsMetabolic Dysfunction-Associated Steatotic Liver DiseaseLiver DiseasesCholangitis, Sclerosing

Other Information

ATC CodeN/A
Related LinksN/A