Idursulfase

艾杜硫酯酶

Report date: 2023/09/12 17:53:40
First In Class

Base Information

Drug NameIdursulfase
Drug Alias NameIdursulfasum艾度硫酸酯酶伊度硫酸酯酶idursulfase-ITRecombinant-iduronate-2-sulfatase(Takeda) +[13] 
ClassificationBiologics > Protein drugs > Enzyme > Recombinant enzymeBiologics > Protein drugs > Recombinant protein > Recombinant enzyme
Mechanisms of ActionDermatan sulfate degradersHeparan sulfate degradersIduronate-2-sulfatase replacements
TargetsDermatan sulfateHeparan sulfateIduronate-2-sulfatase
Therapy Area/IndicationsMucopolysaccharidosis II
Global Approved IndicationsMucopolysaccharidosis II
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date2006/07/24
Country/TerritoryCanadaUnited StatesSweden +[14] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesShire Development Llc
China Registration ClassN/A

Develop Information

Active CompaniesShireTakeda Pharmaceuticals USA IncSanofi +[7] 
Inactive CompaniesN/A
Active IndicationsMucopolysaccharidosis II
Inactive IndicationsN/A

Other Information

ATC CodeA16AB09
Related LinksWikipediaDrugBankKEGG