Troriluzole

曲鲁唑

Report date: 2025/11/10 13:37:44
NME

Base Information

Drug NameTroriluzole
Drug Alias NameTroriluzole hydrochlorideTrigriluzoletrigriluzoleDazlumaBHV-4157a +[7] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionGlutamate release inhibitorsExcitatory amino acids antagonistsVoltage-gated sodium channels blockers +[4] 
TargetsExcitatory amino acidsVoltage-gated sodium channels
Therapy Area/IndicationsSkin MelanomaSolid tumoursObsessive-Compulsive Disorder +[18] 
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryCanadaUnited StatesNetherlands +[11] 
CombinationsNo
Global Highest StatusNDA/BLA
Highest Status in ChinaPhase 3 Clinical
Originator CompaniesYale University
China Registration ClassN/A

Develop Information

Active CompaniesSharp Clinical Services IncBiohaven LtdBioshin Hong Kong Ltd +[11] 
Inactive CompaniesDana-Farber Cancer Institute
Active IndicationsSkin MelanomaSolid tumoursObsessive-Compulsive Disorder +[17] 
Inactive IndicationsAnxiety Disorders

Other Information

ATC CodeN/A
Related LinksWikipediaDrugBankKEGG