Elexacaftor/ivacaftor/tezacaftor

N/A

Report date: 2023/10/19 17:36:28
NME

Base Information

Drug NameElexacaftor/ivacaftor/tezacaftor
Drug Alias NameVX445/TEZ/IVAVX 445/ivacaftor/tezacaftorTezacaftor/VX445/ivacaftorIvacaftor/tezacaftor/VX 445Trikafta +[9] 
ClassificationSmall molecules
Mechanisms of ActionCystic fibrosis transmembrane conductance regulator stimulantsP-glycoprotein 1 inhibitors
TargetsCystic fibrosis transmembrane conductance regulatorP-glycoprotein 1
Therapy Area/IndicationsCystic Fibrosis
Global Approved IndicationsCystic Fibrosis
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date2019/10/21
Country/TerritoryCzechiaBelgiumCanada +[20] 
CombinationsYes TezacaftorElexacaftorIvacaftor
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesVertex Pharmaceuticals Incorporated
China Registration ClassN/A

Develop Information

Active CompaniesVertex Pharmaceuticals IncorporatedVertex Pharmaceuticals (Ireland) Ltd
Inactive CompaniesN/A
Active IndicationsCystic Fibrosis
Inactive IndicationsN/A

Other Information

ATC CodeR07AX
Related LinksKEGG