Botulinum toxin A

A型肉毒毒素

Report date: 2026/05/20 20:02:01

Base Information

Drug NameBotulinum toxin A
Drug Alias Name肉毒杆菌毒素ABotulinum toxin A (Allergan)Onabotulinum toxin AOnabotA XOnabotulinumtoxinA +[12] 
ClassificationBiologics > Protein drugs > Toxin
Mechanisms of ActionSynaptosomal-associated protein 25 inhibitors
TargetsSynaptosomal-associated protein 25
Therapy Area/IndicationsNasolabial fold wrinklesUpper and lower limb spasticityGlabellar lines +[122] 
Global Approved IndicationsNasolabial fold wrinklesGlabellar linesHyperhidrosis +[12] 
Approved Indications in ChinaNasolabial fold wrinkles
Original Approved Country/TerritoryUnited States
Original Approved Date1991/12/09
Country/TerritoryCzechiaBelgiumCanada +[45] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesAllergan PlcAbbvie Inc
China Registration ClassN/A

Develop Information

Active CompaniesHospital Felicio RochoLomonosov Moscow State University Medical Research And Educational CenterUniversity of Texas Southwestern Medical Center +[47] 
Inactive CompaniesUtah State UniversityIrccs National Neurological Institute "C. Mondino" FoundationUniversity of California Irvine +[54] 
Active IndicationsNasolabial fold wrinklesUpper and lower limb spasticityGlabellar lines +[57] 
Inactive IndicationsHemorrhagic StrokeSomatoform DisordersBorderline Personality Disorder +[65] 

Other Information

ATC CodeM03AX01
Related LinksWikipediaDrugBankKEGG