Cyclophosphamide

环磷酰胺

Report date: 2026/05/13 20:02:10
NME

Base Information

Drug NameCyclophosphamide
Drug Alias Name环磷醯胺cyclophosphamidumciclofosfamida环磷胺Procytox +[41] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionAlkylating agentsDNA inhibitors
TargetsDNA
Therapy Area/IndicationsRejection of organ transplantationMetastatic breast cancerSkin Melanoma +[93] 
Global Approved IndicationsNephrosis, LipoidLung NeoplasmsHead and Neck Neoplasms +[20] 
Approved Indications in ChinaLung NeoplasmsHead and Neck NeoplasmsTesticular Neoplasms +[12] 
Original Approved Country/TerritoryUnited States
Original Approved Date1959/11/16
Country/TerritoryCzechiaBelgiumCanada +[43] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesBaxter International Inc
China Registration ClassN/A

Develop Information

Active CompaniesDana-Farber Cancer InstituteDkms Life Gemeinnützige GmbhEuropean Institute Of Oncology +[16] 
Inactive CompaniesImmetacyte LtdBostwick LaboratoriesRadboud University Medical Center +[49] 
Active IndicationsGraft vs Host DiseaseScleroderma, SystemicPrimary Myelofibrosis +[45] 
Inactive IndicationsRejection of organ transplantationMetastatic breast cancerSkin Melanoma +[48] 

Other Information

ATC CodeL01AA01
Related LinksWikipediaDrugBankKEGG