(-)-Epigallocatechin gallate

表没食子儿茶素没食子酸酯

Report date: 2025/05/13 16:53:05
NME

Base Information

Drug Name(-)-Epigallocatechin gallate
Drug Alias Name表没食子儿茶酚没食子酸酯Epigallocatechin gallate绿茶萃取抗氧化物Epigallocatechin-3-gallateEGCG +[9] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionProteasome inhibitorsAMP-activated protein kinases activatorsBeta amyloid A4 protein aggregation inhibitors +[19] 
TargetsProteasomeAMP-activated protein kinasesBeta amyloid A4 protein +[17] 
Therapy Area/IndicationsInflammationFrailtyObesity +[24] 
Global Approved IndicationsN/A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryN/A
Original Approved DateN/A
Country/TerritoryUnited StatesItalyGermany +[5] 
CombinationsNo
Global Highest StatusPhase 2 Clinical
Highest Status in ChinaPhase 2 Clinical
Originator CompaniesCharite Universitaetsmedizin Berlin
China Registration ClassClass 1 Chemical Drug in China

Develop Information

Active CompaniesJinan Fourth People'S HospitalUniversity of Texas Southwestern Medical CenterVertero Therapeutics Inc +[13] 
Inactive CompaniesCharite University, Berlin, GermanyNational Cancer InstituteFriend Of The Catholic University Of The Sacred Heart Of Milan Inc +[6] 
Active IndicationsInflammationFrailtyUterine Cervical Diseases +[12] 
Inactive IndicationsObesityInsulin ResistanceDiabetes Mellitus, Type 2 +[12] 

Other Information

ATC CodeN/A
Related LinksWikipedia