Pemetrexed Disodium Hydrate

培美曲塞二钠

Report date: 2024/05/06 14:41:07
NME

Base Information

Drug NamePemetrexed Disodium Hydrate
Drug Alias NamePemetrexedum培美曲唑培美曲噻培美曲塞二钠水合物Rolazar +[11] 
ClassificationSmall molecules > Heterocyclic drugs
Mechanisms of ActionGAR transformylase inhibitorsThymidylate synthase inhibitorsDihydrofolate reductase inhibitors
TargetsDihydrofolate reductaseGAR transformylaseThymidylate synthase
Therapy Area/IndicationsCNS Embryonal TumorSolid tumoursCentral Nervous System Lymphoma +[50] 
Global Approved IndicationsCarcinoma, Non-Small-Cell LungMesotheliomaSolitary Fibrous Tumor, Pleural
Approved Indications in ChinaMesothelioma
Original Approved Country/TerritoryUnited States
Original Approved Date2004/02/04
Country/TerritoryCzechiaBelgiumBulgaria +[40] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaApproved
Originator CompaniesEli Lilly And Company
China Registration ClassN/A

Develop Information

Active CompaniesLilly France SasEli Lilly And CompanyJiangsu Hansoh Pharmaceutical Group Co Ltd +[6] 
Inactive CompaniesNovocure LtdKorea Research Institute Of Bioscience & BiotechnologyDana-Farber Cancer Institute +[16] 
Active IndicationsSolid tumoursUrinary Bladder NeoplasmsCarcinoma, Non-Small-Cell Lung +[7] 
Inactive IndicationsCNS Embryonal TumorCentral Nervous System LymphomaLymphoproliferative Disorders +[43] 

Other Information

ATC CodeL01BA04
Related LinksWikipediaDrugBankKEGG