Olipudase alfa

奥立扑酶α

Report date: 2026/04/14 20:00:15
First In Class

Base Information

Drug NameOlipudase alfa
Drug Alias NameOlipudase alpha奥利普达酶αRecombinant human acid sphingomyelinase奥立扑酶αolipudase alfa +[13] 
ClassificationBiologics > Protein drugs > Enzyme > Recombinant enzymeBiologics > Protein drugs > Recombinant protein > Recombinant enzyme
Mechanisms of ActionSphingomyelinase replacements
TargetsSphingomyelin
Therapy Area/IndicationsNiemann-Pick Disease, Type BNiemann-Pick Disease, Type ANiemann-Pick Diseases
Global Approved IndicationsNiemann-Pick Disease, Type BNiemann-Pick Disease, Type A
Approved Indications in ChinaN/A
Original Approved Country/TerritoryJapan
Original Approved Date2022/03/28
Country/TerritoryBelgiumBulgariaUnited States +[18] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesGenzyme Corp
China Registration ClassN/A

Develop Information

Active CompaniesSanofi-Aventis GroupeSanofiGenzyme Corp +[4] 
Inactive CompaniesN/A
Active IndicationsNiemann-Pick Disease, Type BNiemann-Pick Disease, Type ANiemann-Pick Diseases
Inactive IndicationsN/A

Other Information

ATC CodeN/A
Related LinksDrugBankKEGG