Bezlotoxumab

贝洛度尤单抗

Report date: 2024/06/06 10:45:19
First In Class

Base Information

Drug NameBezlotoxumab
Drug Alias NameBezlotoxumabum贝洛托人单抗贝洛托舒单抗Clostridium difficile toxin B monoclonal antibodyZinplava +[9] 
ClassificationBiologics > Protein drugs > Immunoglobulin > Antibody > Monoclonal antibody > Monoclonal antibody human
Mechanisms of ActionToxin B inhibitorsBotulinum toxin inhibitors
TargetsToxin BBotulinum toxin
Therapy Area/IndicationsDiarrheaMultiple Organ FailureDeath +[5] 
Global Approved IndicationsDiarrheaClostridium Infections
Approved Indications in ChinaN/A
Original Approved Country/TerritoryUnited States
Original Approved Date2016/10/21
Country/TerritoryCzechiaCanadaUnited States +[21] 
CombinationsNo
Global Highest StatusApproved
Highest Status in ChinaN/A
Originator CompaniesMerck Sharp & Dohme Corp
China Registration ClassN/A

Develop Information

Active CompaniesThe Brigham and Women's HospitalMerck Sharp & Dohme CorpMerck Sharp & Dohme Bv +[6] 
Inactive CompaniesMedarex Inc
Active IndicationsDiarrheaMultiple Organ FailureDeath +[5] 
Inactive IndicationsN/A

Other Information

ATC CodeJ06BB21
Related LinksWikipediaKEGG